国产一卡2卡三卡4卡麻豆_了解最新日韩草逼视频_h片在线播放一区_国产激情影视在线_好了av四色综合无码久久_欧美黑白双插OOR720P_日本精品中文字幕在线_秋霞午夜手机影院_亚洲国产一区二区3da毛片_欧美杂交深喉video中文字幕

BPS Bioscience Inc.
中級會員 | 第2年

當前位置:BPS Bioscience Inc.>>試劑>>藥物篩選>> SRT1720

SRT1720

參  考  價面議
具體成交價以合同協議為準

產品型號

品       牌BPS Bioscience

廠商性質生產商

所  在  地

更新時間:2023-12-19 23:35:35瀏覽次數:118次

聯系我時,請告知來自 化工儀器網
同類優質產品更多>
保存條件:Roomtemp
  • 保存條件:

    Room temp. (continental US) or gel packs

  • 保質期:

    Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

  • 英文名:

    SRT1720

  • 數量:

    1

  • 供應商:

    BPS Bioscience Inc.

  • CAS號:

    /

  • 規格:

    5 mg

SRT1720 is a small-molecule compound which has the ability of activating the sirtuin subtype SIRT1 in vitro. SRT1720 has similar activity in the body to the known SIRT1 activator resveratrol, but is 1000x more potent. It affects mitochondrial respiration in a Sirt1- and PGC-1α-dependent manner. SRT1720 has been demonstrated to enhance insulin sensitivity and improve measures of mitochondrial capacity and oxidative metabolism. Treatment of multiple myeloma (MM) cells with SRT1720 inhibits growth and induced apoptosis in MM cells resistant to conventional and bortezomib therapies without significantly affecting the viability of normal cells. SRT1720 is able to enhance the cytotoxic activity of bortezomib or dexamethasone. Anti-MM activity of SRT1720 is related to: 1) activation of caspase-8, caspase-9, caspase-3, poly(ADP) ribose polymerase; 2) increase in reactive oxygen species; 3) induction of phosphorylated ataxia telangiectasia mutated/checkpoint kinase 2 signaling; 4) decrease in vascular endothelial growth factor-induced migration of MM cells and associated angiogenesis; and 5) inhibition of nuclear factor-κB.
溫馨提示:不可用于臨床治療。

會員登錄

×

請輸入賬號

請輸入密碼

=

請輸驗證碼

收藏該商鋪

X
該信息已收藏!
標簽:
保存成功

(空格分隔,最多3個,單個標簽最多10個字符)

常用:

提示

X
您的留言已提交成功!我們將在第一時間回復您~
撥打電話
在線留言
主站蜘蛛池模板: 东乡县| 临夏市| 江北区| 乐亭县| 通辽市| 绥化市| 漳州市| 安远县| 油尖旺区| 平凉市| 蒙城县| 平和县| 祁连县| 汾阳市| 玉屏| 博湖县| 凭祥市| 伽师县| 鲁山县| 怀柔区| 安乡县| 榆树市| 绥宁县| 新沂市| 吐鲁番市| 南部县| 临漳县| 娱乐| 兖州市| 灵璧县| 屯昌县| 富阳市| 长春市| 达尔| 吉水县| 铁岭县| 兴宁市| 阿拉善左旗| 科技| 河池市| 米脂县|