MCE 的所有產品僅用作科學研究或藥證申報，我們不為任何個人用途提供產品和服務。

gamma-DGG

CAS No. : 6729-55-1

產品活性：gamma-DGG is a competitive AMPA receptor blocker.

研究領域：Membrane Transporter/Ion Channel  |  Neuronal Signaling

作用靶點：iGluR

In Vitro: gamma-DGG (γ-DGG), a competitive AMPA receptor blocker that blocks less at higher glutamate concentration. At 200-400 μM, gamma-DGG in the bath reduces the miniature EPSC (mEPSC) amplitude by 26±2% (n=5 synapses), and shifts both the mEPSC amplitude distribution and the cumulative probability curve to the left. gamma-DGG (γ-DGG) is the most effective antagonist of the excitatory post-synaptic potentials (e.p.s.p.s). Its action is reversible and not associated with any change in the passive membrane properties of the granule cells or in the apparent reversal potential of the e.p.s.p. Quantal analysis shows that the reduction in the e.p.s.p. paralleled the decrease in quantal size rather than quantal content, confirming a post-synaptic site of the action of gamma-DGG.

相關產品：Bioactive Compound Library Plus  |  Membrane Transporter/Ion Channel Compound Library  |  Neuronal Signaling Compound Library  |  Neurotransmitter Receptor Compound Library  |  Neuroprotective Compound Library  |  Anti-Parkinson's Disease Compound Library  |  Neurodegenerative Disease-related Compound Library  |  Targeted Diversity Library  |  Antidepressant Compound Library  |  Membrane Protein-targeted Compound Library  |  Membrane Receptor-targeted Compound Library  |  6-Methoxy-2-naphthoic acid  |  NMDA receptor modulator 4  |  CIQ  |  Budipine  |  Glycine-¹⁵N,d₂  |  AMPA receptor modulator-3  |  ZL006  |  Orphenadrine hydrochloride  |  AMPA receptor modulator-2  |  (S)-Willardiine  |  Kynurenic acid-d₅  |  Fanapanel  |  Ifenprodil tartrate  |  GluN2B receptor modulator-1  |  Decanoic acid-d₂  |  Coluracetam  |  Caroverine hydrochloride  |  L-Phenylalanine-d  |  Dynorphin A (1-10) (TFA)  |  L-Glutamic acid-d₅  |  JAMI1001A  |  Sepimostat  |  NMDA  |  CFM-2  |  Cyclothiazide  |  JNJ-61432059  |  DQP-1105  |  L-Glutamic acid-¹³C₅,¹⁵N,d₅  |  SYM 2081  |  Cycloleucine

熱門產品線：重組蛋白  |  化合物庫  |  天然產物  |  熒光染料  |  PROTAC  |  同位素標記物  |  寡核苷酸  |  抗體  |  點擊化學

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides  |  Antibodies  |  Click Chemistry

品牌介紹:
•   MCE (MedChemExpress) 擁有200 多種全球僅有化合物庫，我們致力于為全球科研客戶提供前沿的高品質小分子活性化合物；
•   50,000 多種高選擇性抑制劑、激動劑涉及各熱門信號通路及疾病領；
•   產品種類涵蓋各種重組蛋白，多肽，常用試劑盒 ，更有 PROTAC、ADC 等特色產品，廣泛應用于新藥研發、生命科學等科研項目；
•   提供虛擬篩選，離子通道篩選，代謝組學分析檢測分析，藥物篩選等專業技術服務；
•   設有專業的實驗中心和嚴格的質控、驗證體系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各項質檢報告，確保產品的高純度、高品質；
•   產品的生物活性多經各國客戶實驗驗證；
•   Nature, Cell, Science 等多種頂級期刊及制藥 Patent 收錄了MCE客戶的科研成果；
•   專業團隊跟蹤最新的制藥及生命科學研究進展，為您提供全球新的活性化合物；
•   與世界各大制藥公司及著名科研機構建立了長期的合作。