MCE 的所有產品僅用作科學研究或藥證申報，我們不為任何個人用途提供產品和服務。

PF-04979064

CAS No. : 1220699-06-8

產品活性：PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with K_is of 0.13 nM and 1.42 nM for PI3Kα and mTOR, respectively.

研究領域：PI3K/Akt/mTOR

作用靶點：PI3K  |  mTOR

In Vitro: PF-04979064 is tested against human class I PI3K isoforms PI3Kα, PI3Kγ, and PI3Kδ, with PI3Kα K_i of 0.13 nM, PI3Kγ K_i of 0.111 nM, and PI3Kδ K_i of 0.122 nM.

In Vivo: PF-04979064 is progressed to rat in vivo PK studies and exhibits robust PK profile: Vdss=5.23 L/kg, Cl=19.3 mL/min/kg, T_1/2=1.85 h, and F%=61%.

相關產品：Bioactive Compound Library Plus  |  Kinase Inhibitor Library  |  PI3K/Akt/mTOR Compound Library  |  Stem Cell Signaling Compound Library  |  Anti-Cancer Compound Library  |  Autophagy Compound Library  |  Anti-Aging Compound Library  |  Antioxidant Compound Library  |  Differentiation Inducing Compound Library  |  Reprogramming Compound Library  |  Oxygen Sensing Compound Library  |  Glycolysis Compound Library  |  Cytoskeleton Compound Library  |  Anti-Breast Cancer Compound Library  |  Anti-Lung Cancer Compound Library  |  Anti-Pancreatic Cancer Compound Library  |  Anti-Blood Cancer Compound Library  |  Anti-Cancer Metabolism Compound Library  |  Anti-Obesity Compound Library  |  Angiogenesis-Related Compound Library  |  Glucose Metabolism Compound Library  |  Anti-Liver Cancer Compound Library   |  Anti-Colorectal Cancer Compound Library   |  Anti-Prostate Cancer Compound Library  |  Anti-Pulmonary Fibrosis Compound Library  |  Cancer Stem Cells Compound Library  |  Heterocyclic Compound Library  |  Pain-Related Compound Library  |  Mitochondrial Protection Compound Library  |  Membrane Protein-targeted Compound Library  |  D-α-Hydroxyglutaric acid disodium  |  Umbralisib hydrochloride  |  PI3K-IN-22  |  Rigosertib sodium  |  PI3Kδ/γ-IN-2  |  PI3kδ inhibitor 1  |  WYE-354  |  GSK2292767  |  PI3K-IN-28  |  PI3K/mTOR Inhibitor-13  |  Disitertide diammonium  |  1,3-Dicaffeoylquinic acid  |  Palomid 529  |  Quercetin dihydrate  |  PI3Kγ inhibitor 4  |  PI-103 Hydrochloride  |  Hirsutenone  |  (+)-Usnic acid  |  Sophocarpine monohydrate  |  Heterophyllin B  |  IC-87114  |  Phosphatidylinositol 4,5-bisphosphate  |  Chaetominine  |  SF2523  |  Flupentixol  |  8-Aminoadenosine  |  GNE-490  |  MHY-1685  |  AZD-7648  |  Serabelisib

熱門產品線：重組蛋白  |  化合物庫  |  天然產物  |  熒光染料  |  PROTAC  |  同位素標記物  |  寡核苷酸  |  抗體  |  點擊化學

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides  |  Antibodies  |  Click Chemistry

品牌介紹:
•   MCE (MedChemExpress) 擁有200 多種全球僅有化合物庫，我們致力于為全球科研客戶提供前沿的高品質小分子活性化合物；
•   50,000 多種高選擇性抑制劑、激動劑涉及各熱門信號通路及疾病領；
•   產品種類涵蓋各種重組蛋白，多肽，常用試劑盒 ，更有 PROTAC、ADC 等特色產品，廣泛應用于新藥研發、生命科學等科研項目；
•   提供虛擬篩選，離子通道篩選，代謝組學分析檢測分析，藥物篩選等專業技術服務；
•   設有專業的實驗中心和嚴格的質控、驗證體系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各項質檢報告，確保產品的高純度、高品質；
•   產品的生物活性多經各國客戶實驗驗證；
•   Nature, Cell, Science 等多種頂級期刊及制藥 Patent 收錄了MCE客戶的科研成果；
•   專業團隊跟蹤最新的制藥及生命科學研究進展，為您提供全球新的活性化合物；
•   與世界各大制藥公司及著名科研機構建立了長期的合作。