TULA Polyclonal Antibody

抗體，也叫免疫球蛋白（Ig），是一種能特異性結合抗原的糖蛋白，而抗原是在易感染動物體內引發抗體產生的物質。在體內，抗體是由于外源性分子的侵襲而產生的。抗體以一個或者多個Y字形單體存在，每個Y字形單體由4條多肽鏈組成，包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈是根據它們的分子量大小來命名的。Y字形結構的頂端是可變區，為抗原結合部位。任何一個抗體的輕鏈都可以分為κ或λ型（基于小分子多肽結構上的差異），每一個抗體的重鏈則決定了它的類或型。

產品詳情

TULA Polyclonal Antibody detects endogenous levels of TULA protein.

免疫原詳細信息

The antiserum was produced against synthesized peptide derived from human UBASH3A. AA range:311-360

相關試劑

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

背景

This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

備注：圖片僅供參考。僅供科研，不可用于臨床。