Normal Human Glomerular Endothelial Cells
人腎小球內皮細胞
Normal Human Glomerular Endothelial Cells (NhGEC) are specialized microvascular cells that make up the innermost layer of the glomerular filtration barrier. They are separated from podocytes by a thin layer of glomerular basement membrane. These cells exhibit cobblestone morphology at confluence and present fenestrations specific of this cell type.
The NhGEC are obtained after cortex digestion, and single glomerular isolation. Glomeruli are further digested and then NhGEC are isolated by CD31 positive selection as a pure population.
The NhGEC express factor VIII-related antigen, angiotensin converting enzyme activity, and endocytosed acetylated low-density lipoproteins. They are also characterized by the presence of intracellular Weibel-Palade bodies and caveolae and microvillous projections on the luminal surface.
The NhGEC will be evaluated for the expression of endothelial specific markers (e.g. CD31, vWF and Ve-Cadherin) by immunofluorescence.
NhGEC can be expanded between 5 to 8 passages, while maintaining their particular characteristics.
NhGEC are terminally differentiated cells and present no significant differentiation capacity.
The NhGEC are for research use only and not approved for human use, or for in vitro diagnostic testing.
Normal Human Glomerular Endothelial Cells
人腎小球內皮細胞
PBMC分離試劑盒
人外周血單個核細胞分離試劑盒PBMC分離液
人PBMC分離試劑盒 人PBMC分離液
猴外周血單個核細胞分離試劑盒PBMC分離液
猴PBMC分離試劑盒 猴PBMC分離液
比格犬外周血單個核細胞分離試劑盒PBMC分離液
比格犬PBMC分離試劑盒 比格犬PBMC分離液
狗外周血單個核細胞分離試劑盒PBMC分離液
狗PBMC分離試劑盒 狗PBMC分離液
大鼠外周血單個核細胞分離試劑盒PBMC分離液
大鼠PBMC分離試劑盒 大鼠PBMC分離液
小鼠外周血單個核細胞分離試劑盒PBMC分離液
小鼠PBMC分離試劑盒 小鼠PBMC分離液
兔外周血單個核細胞分離試劑盒PBMC分離液
兔PBMC分離試劑盒 兔PBMC分離液
豬外周血單個核細胞分離試劑盒PBMC分離液
豬PBMC分離試劑盒 豬PBMC分離液
豚鼠外周血單個核細胞分離試劑盒PBMC分離液
豚鼠PBMC分離試劑盒 豚鼠PBMC分離液
骨髓單個核細胞分離試劑盒Bone Marrow Mononuclear Cells Isolation Kit
脾單個核細胞分離試劑盒 Spleen Mononuclear Cells Isolation Kit
紅細胞分離試劑盒
人紅細胞分離試劑盒 紅細胞分離液
猴紅細胞分離試劑盒 紅細胞分離液
比格犬紅細胞分離試劑盒 紅細胞分離液
大鼠紅細胞分離試劑盒 紅細胞分離液
小鼠紅細胞分離試劑盒 紅細胞分離液
ADME相關產品
Ⅰ相代謝穩定性試劑盒
Ⅱ相代謝穩定性試劑盒
CYP450 酶代謝表型研究試劑盒(化學抑制法/7種抑制劑)
CYP450 酶代謝表型研究試劑盒(重組酶法/7種酶)
CYP450 酶代謝表型研究試劑盒(重組酶法/單酶)
酶抑制(IC50)研究試劑盒(7種特異性底物)
酶抑制(IC50)研究試劑盒(單個酶)
NADPH再生系統
UGT孵育系統
0.1M PBS
肝微粒體(人,猴,犬,大鼠,小鼠)
肝S9(人,猴,犬,大鼠,小鼠)
肝原代細胞(人,猴,犬,大鼠,小鼠)
CYP450(CYP1A2,CYP2A6,CYP2B6,CYP2C8,CYP2C9,CYP2C19,CYP2D6,CYP2E1,CYP3A4)
UGT酶
探針底物,代謝產物,抑制劑(CYP1A2,CYP2A6,CYP2B6,CYP2C8,CYP2C9,CYP2C19,CYP2D6,CYP2E1,CYP3A4)
ADME服務項目
肝微粒體代謝穩定性(人,猴,犬,大鼠,小鼠)
肝細胞代謝穩定性試驗(人,猴,犬,大鼠,小鼠)
代謝表型研究
代謝產物鑒定
代謝途徑鑒定
種屬比較研究
CYPP450抑制實驗(CYP1A2,CYP2A6,CYP2C9,CYP2C19,CYP2D6,CYP2E1,CYP3A4)
CYPP450誘導實驗
血漿蛋白結合率測定
血漿穩定性試驗
跨膜轉運試驗
藥物-藥物相互作用
毒理學研究
Innovative Reagents for Innovative Research
匯智和源致力于為創新藥企業及生命科學研究機構提供高品質的生物試劑。