目錄:愛必信(上海)生物科技有限公司>>細胞生物學>>重組蛋白>> abs04222Recombinant Mouse TGF-β1 Protein
CAS | - | 純度 | - |
---|---|---|---|
分子量 | - | 分子式 | - |
供貨周期 | 現貨 | 規格 | 10ug;50ug |
貨號 | abs04222 | 應用領域 | 生物產業,綜合 |
主要用途 | - |
概述 | |
描述 | Recombinant Mouse Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed. |
別名 | TGFβ1蛋白;TGFB1蛋白;TGF-beta-1; CED; DPD1; TGFB; TGF-b1; TGFB1; CEDLAP; latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1 |
種屬 | Mouse |
來源 | Human Cells |
形態 | Lyophilized from a 0.2 μm filtered solution of 4mM Hcl |
性能 | |
序列 | ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALY NQHNPGASASPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS |
標簽 | No Tag |
純度 | Greater than 95% as determined by reducing SDS-PAGE. |
內毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
活性 | Measured by its ability to inhibit IL-4-dependent proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is 5-25 pg/ml. |
溶解方法 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in 4mM Hcl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
儲存/保存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
靶標 | |
背景說明 | Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system. |
Accession | P04202 |