Sulfo-EGS、LC-SPDP、Sulfo-LC-SPDP、Sulfo-MBS上百種交聯劑

         交聯劑是一類小分子化合物，具有2個或者更多的針對基團（-NH2、-COOH、-HS等）的反應性末端，可以和2個或者更多的分子分別偶聯，從而使這些分子結合在一起。70年代時人們普遍使用戊二醛作為交聯劑連接抗體和指示劑（如酶類），但其缺點是由于交聯基團是隨機的，容易形成雜亂的多聚體。80年代，更具選擇性的交聯劑,例如NHS（針對-COOH）和馬來酰亞胺（針對-HS)在生命科學研究中得到了更為的應用。巧妙地運用交聯劑可以在相互作用研究，學，癥等領域取得意想之外的收獲。截2010年，市面常用的交聯劑大約有一百多種。

 供應產品詳情：

Sulfo-EGS

西安齊岳生物科技有限公司提供Sulfo-EGS交聯試劑產品。

Sulfo-EGS crosslinker, Ethylene glycolbis(sulfosuccinimidylsuccinate), is a water soluble homobifunctionalcrosslinker. The 12-atom spacer arm of the Sulfo-EGS crosslinking reagent is cleavable.The Sulfo-EGS spacer arm is cleaved by hydroxylamine at pH 8.5 for 3-6 hours at 37°C. The Sulfo-EGS protein crosslinker possesses amino reactive Sulfo-NHS esters on both ends of the

molecule and can be used to label cell surface proteins, since the molecule is not cell membrane

permeable.

Alternative Names: Ethylene glycol bis (sulfosuccinimidylsuccinate); Ethylene Glycol-Bis (Succinic Acid N-Hydroxysulfosuccinimide Ester)

Molecular Weight: 660.45

包裝：100mg，500mg

保存：-20°

貨期：3-4周

LC-SPDP

西安齊岳生物科技有限公司提供LC-SPDP交聯試劑產品。

LC-SPDP crosslinker is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. The "long chain" LC-SPDP crosslinking reagent has a 15.7

angstrom spacer arm, compared to the 6.8 angstrom spacer arm of SPDP.

Alternative Name: Succinimidyl-6-(3-[2-pyridyldithiol-propionamido) hexanoate

Molecular Weight: 425.5

包裝：100mg，500mg

保存：-20°

貨期：3-4周

Sulfo-LC-SPDP

西安齊岳生物科技有限公司提供Sulfo-LC-SPDP交聯試劑產品。

Sulfo-LC-SPDP crosslinking reagent is a cleavable, water soluble, amino and thiol (sulfhydryl)

reactive heterobifunctional protein crosslinker.

Alternative Name: Sulfosuccinimidyl-6-(3’-[2-pyridyldithio]-propionamido) hexanoate

Molecular Weight: 527.6

包裝：100mg，500mg

保存：-20°

貨期：3-4周

Sulfo-MBS

西安齊岳生物科技有限公司提供Sulfo-MBS交聯試劑產品。

Sulfo-MBS crosslinker (m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester) is a non-cleavable, water soluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The Sulfo-MBS crosslinking reagent's NHS ester and maleimide reactive groups react with amine and sulfhydryl moites, respectively. MBS crosslinker is the water insoluble analog which is also offered by ProteoChem.

Alternative Names: 3-Maleimidobenzoic acid N-hydroxysulfosuccinimide ester; meta-

Maleimidobenzoyl-N-hydroxysulfosuccinimide ester

Molecular Weight: 416.3

包裝：100mg，500mg

保存：-20°

貨期：3-4周

Sulfo-SANPAH

西安齊岳生物科技有限公司提供Sulfo-SANPAH交聯試劑產品。

Sulfo-SANPAH crosslinker (N-Sulfosuccinimidyl-6-[4'-azido-2'-nitrophenylamino] hexanoate) is

a water soluble, heterobifunctional protein crosslinker with a spacer arm length of 18.2 Å.

Sulfo-SANPAH crosslinking reagent contains an NHS ester that reacts with primary amines

and a nitrophenylazide group that is photoreactive at 320-350 nm toward amino groups.

Alternative Name: 1-[6-[(4-azido-2-nitro-phenyl)amino]hexanoyloxy]-2,5-dioxo-pyrrolidine-3-sulfonic acid

CAS #: 102568-43-4

Molecular Weight: 492.4

包裝：100mg，500mg

保存：-20°

貨期：3-4周

Sulfo-SMCC

西安齊岳生物科技有限公司提供ulfo-SMCC交聯試劑產品。

Sulfo-SMCC crosslinker (Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate)

is a water soluble, heterobifunctional crosslinker. Sulfo-SMCC crosslinking reagent has an 8.3

angstrom non-cleavable spacer arm and its maleimide group reacts with sulfhydryls (thiols),

while the Sulfo-NHS ester is reactive toward primary amines. Sulfo-SMCC can be used to produce antibody-protein crosslinked conjugates or efficiently label cell surface proteins.

Alternative Name:

4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-Nhydroxysuccinimide ester

CAS #: 92921-24-9

Molecular Weight: 436.4

包裝：100mg

保存：-20°

貨期：3-4周

Biotin Hydrazide

西安齊岳生物科技有限公司提供Biotin Hydrazide交聯試劑產品。

Biotin Hydrazide (Biotin-Hz) is a carbohydrate reactive biotinylation reagent. Biotin Hydrazide

is a great choice for labeling mouse monoclonal antibodies, lectins, sugars, unpaired cytosine

residues in nucleic acids, and glycoprotiens. Typically, Biotin Hydrazide is used for coupling glycoproteins through the carbohydrate by hydrazone formation.

Alternative Name: (+)-Biotin Hydrazide

CAS #: 66640-86-6

Molecular Weight: 258.3

包裝：100mg

保存：-20°

貨期：3-4周

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