13129540117
當前位置：深圳欣博盛生物科技有限公司>>蛋白&肽>> α2-Macroglobulin (human plasma), (purified)
IL-38 (aa 3-152) (mouse) (rec.) 蛋白
DNER (extracellular domain) (human)
| 供貨周期 | 兩周 | 規格 | 1*1mg |
|---|---|---|---|
| 貨號 | BML-SE502-0001 | 應用領域 | 生物產業 |
| 主要用途 | 科研 |
α2-Macroglobulin (human plasma), (purified)
| MW: | 725 kDa |
| Source: | Isolated from human plasma that is tested to be negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2. |
| UniProt ID: | P01023 |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | In addition to binding TGF-β and β-amyloid, α2-macroglobulin covalently binds and inhibits a wide range of proteases, including ADAMs, calpains, cathepsins, chymase, clotting factors, kallikreins, MMPs, neutrophil elastase, and proteinase 3. It also plays a role in the innate immune system, inhibiting parasitic proteases. When treated with methylamine, it blocks binding of apoE to lipoprotein receptor-related protein (LRP). |
| Regulatory Status: | RUO - Research Use Only |
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