T淋巴細胞激活蛋白抗體

英文名稱 Sca1
中文名稱 T淋巴細胞激活蛋白抗體
別    名 Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Stem cell antigen 1; Sca1 / Ly6A/E; SCA-1; T-cell-activating protein; TAP; Ly6al; Ly6a; LY6A_MOUSE.
   
說 明 書 0.1ml  0.2ml  
研究領域 細胞生物  免疫學  細胞膜受體  細胞表面分子  t-淋巴細胞  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat, 
產品應用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11.6kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Sca1/Ly6A/E
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. In the periphery, Sca1 exhibits a pattern of expression which is based on differences between the two allotypes. Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1+ resting peripheral lymphocytes, whereas Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1+ lymphocytes. The expression of Sca1 is dramatically upregulated in all strains upon cellular activation.

Function:
T-cell activation.

Subcellular Location:
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xy-13763R    KIAA1549KIAA1549蛋白抗體
xy-4643R    KRV-VP1+KRV-VP2 (C-terminus)基爾曼氏細小病毒VP1/VP2抗體(大鼠潛在病毒KRV)C端
xy-7515R    KLHL20Kelch樣蛋白20抗體
xy-5786R    KLST激肽釋放酶抑制劑抗體
xy-5935R    KLHL7kelch樣蛋白7抗體
xy-5933R    KCNK 9TWIK相關酸敏感鉀離子通道蛋白9抗體
xy-5870R    KLK6激肽釋放酶6抗體
xy-5871R    KLK8激肽釋放酶8抗體
xy-5872R    KLKB1血漿激肽釋放酶抗體
xy-6529R    phospho-EZH2 (Thr487)磷酸化抑癌蛋白EZH2抗體
xy-6139R    KDM5B組蛋白去甲基化酶JARID1B抗體
xy-4144R    Keratan Sulfate硫酸角質素抗體
xy-7719R    KRG2角質細胞生長因子調節蛋白2抗體
xy-2886R    KCNG4鉀離子通道蛋白G蛋白4抗體
xy-12178R    KCTD18鉀通道多聚體結構域KCTD18抗體
xy-4900R    KEAP1胞質接頭蛋白Keap1
xy-11861R    KALRN舞蹈癥相關蛋白KALRN抗體
xy-2084R    Kir4.1細胞內流鉀通道蛋白Kir4.1抗體
xy-11864R    KIRREL3腎病樣蛋白3抗體
xy-11865R    KLF7KLF樣轉錄因子7抗體
xy-7868R    KLHL8Kelch樣蛋白8抗體
xy-11728R    KCNQ2鉀離子通道蛋白家族KCNQ2抗體
xy-11729R    KCTD7鉀離子通道多聚體結構域蛋白7抗體
xy-11730R    Kv1.1鉀通道蛋白1抗體
xy-8691R    KCNAB1電壓門控鉀通道蛋白1抗體
xy-11350R    KIF1A微管驅動蛋白家族成員1A抗體
xy-9928R    KCNE1鉀離子通道蛋白家族成員1抗體
xy-9929R    KCNE1L鉀離子通道蛋白家族成員1樣蛋白抗體
xy-9930R    KCNE2鉀離子通道蛋白家族成員2抗體
xy-9931R    KCNJ5G蛋白激活內向鉀通道5抗體