精神障礙相關GAP蛋白抗體

英文名稱 srGAP3
中文名稱 精神障礙相關GAP蛋白抗體
別    名 ARHGAP 14; ARHGAP14; Gbi; ME GAP; MEGAP; Mental disorder associated GAP; Rho GTPase activating protein 14; SLIT ROBO Rho GTPase activating protein 3; srGAP 2; srGAP 3; srGAP2; SRGP 2; SRGP2; WAVE associated Rac GTPase activating protein; WRP.

說 明 書 0.1ml  0.2ml  
研究領域 免疫學  神經生物學  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 121kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human srGAP3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
srGAP3 (SLIT ROBO Rho GTPase-activating protein 3) is a GTPase activating protein (GAP) for the small G protein Rac. It has a putative role in attenuating Rac1 signalling in neurons. srGAP3 is thought to act downstream of the Slit-Robo pathway, which regulates neuronal migration and axonal branching, and play an important role in axonal regeneration after axotomy. It also plays a putative role in severe mental retardation.

Subunit:
Interacts with WASF1. Probably interacts with ROBO1. Interacts with FASLG.

Tissue Specificity:
Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. xy-12176R    phospho-KCNJ1(Ser44)磷酸化細胞內流鉀通道蛋白KCNJ1抗體
xy-12177R    KCNT2鈣激活鉀通道蛋白KCNT2抗體
xy-12179R    KIR5.1細胞內流鉀通道蛋白Kir5.1抗體
xy-12180R    phospho-KIR5.1(Ser416)磷酸化細胞內流鉀通道蛋白Kir5.1抗體
xy-12181R    phospho-Kir6.2(Thr224)磷酸化ATP敏感性鉀通道亞基kir6.2抗體
xy-12182R    KCNA2B電壓門控鉀通道蛋白KVβ.2抗體
xy-12183R    Kv1.4電壓門控性鉀通道蛋白Kv1.4抗體
xy-12184R    Kv1.6電壓門控性鉀通道Kv1.6抗體
xy-12185R    phospho-Kv2.1(Ser805)磷酸化鉀通道蛋白DRK1抗體
xy-12186R    Kv2.2電壓門控性鉀通道Kv2.2抗體
xy-11211R    KIF3A驅動蛋白家族蛋白3抗體
xy-11212R    KLC1驅動蛋白2抗體
xy-8563R    KIAA1522KIAA1522蛋白抗體
xy-9431R    KCTD5鉀離子通道四聚體結構域蛋白5抗體
xy-9504R    KLMW Kininogen高分子量激肽原重鏈抗體
xy-9637R    KCTD11鉀通道四聚體結構域蛋白11抗體
xy-8052R    KLHL26Kelch樣蛋白26抗體
xy-6940R    KDEL (ER Marker)賴氨酸，天冬氨酸，谷氨酸，亮氨酸相關序列抗體
xy-8054R    KLHL10Kelch樣蛋白10抗體
xy-8055R    KLHL11Kelch樣蛋白11抗體
xy-8053R    KLHL3Kelch樣蛋白3抗體
xy-8056R    KLHL14Kelch樣蛋白14抗體
xy-8057R    KLHL31Kelch樣蛋白31抗體
xy-8058R    KLHL32Kelch樣蛋白32抗體
xy-1837R    KCNA5鉀電壓閥門通道混合器相關亞家族成員5抗體
xy-1838R    KLF10TGF-β誘導早期應答基因1抗體
xy-1575R    KCNA3離子通道蛋白Kv1.3抗體
xy-2019R    phospho-KLF5(Ser272)磷酸化KLF5抗體
xy-2020R    phospho-KLF5(Ser275)磷酸化KLF5抗體
xy-1815R    ERG/KCNH2特異性鉀離子通道蛋白抗體