磺酰脲類藥物受體1抗體

英文名稱 SUR1
中文名稱 磺酰脲類藥物受體1抗體
別    名 ABC36; Abcc8; ATP binding cassette sub family C (CFTR/MRP) member 8; ATP binding cassette transporter sub family C member 8 (1); HHF1; HRINS; MRP8; PHHI; Sulfonylurea receptor 1; SUR.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 免疫學(xué)  細(xì)胞膜受體  藥物及化合物  糖尿病  內(nèi)分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Horse, Guinea Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 175kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SUR1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SUR1 is a member of ATP binding cassette super family. SUR receptor confers the sensitivity of Kir6.2 to ATP/ADP sensitivity and to pharmacological agents such as sulfonylurea and diazoxide that close or open the KATP channels. The persistent heyperinsulinimic hypoglycemia in infancy (PHHI) is familial disorder due to defect in negative feed back in response to low glucose levels. SUR1 was mapped on chromosome 11p14-15.1, the same location where the gene for PHHI is located. It has been shown that the expression of Kir6.2 and SUR1 are regulated by glucose levels and the actives of glucogon like peptide receptor 1. Abnormal insulin secretion in PHHI appears to be caused by mutations in the SUR gene.xy-2485R    phospho-JAK2(Tyr1007+Tyr1008)磷酸化蛋白酪氨酸激酶JAK-2抗體
xy-6842R    JMJD6凋亡細(xì)胞清除受體抗體
xy-4601R    phospho-c-Jun(Thr91+Thr93)磷酸化原癌基因c-Jun抗體
xy-4244R    Jagged 2Notch配體Jagged 2蛋白抗體
xy-8178R    Jarid1C組蛋白去甲基化Jarid1C抗體
xy-3824R    JMJD1B組蛋白去甲基轉(zhuǎn)移酶JMJD1B抗體
xy-0702R    Junctophilin-2親聯(lián)蛋白2抗體
xy-12387R    KIF13B驅(qū)動蛋白家族蛋白13B抗體
xy-12388R    KIF7驅(qū)動蛋白家族蛋白7抗體
xy-12395R    KAT3ACREB結(jié)合蛋白抗體
xy-10056R    KNDC1腦蛋白9抗體
xy-12371R    Kindlin 2絲裂原誘導(dǎo)蛋白2抗體
xy-15508R    KLF17鋅指蛋白393抗體
xy-3821R    KDM1組蛋白賴氨酸特異性脫甲基酶1抗體
xy-8177R    KIF11驅(qū)動蛋白樣蛋白1抗體（甲狀腺激素受體相互作用蛋白5）
xy-8170R    KMT3B組蛋白甲基化KMT3B抗體（雄激素受體激活蛋白）
xy-3762R    Kv4.3離子通道蛋白Kv4.3抗體
xy-6893R    KLLN Killin-p53調(diào)節(jié)復(fù)制抑制蛋白抗體
xy-6127R    Lysyl tRNA synthetase賴氨酸t(yī)RNA的連接酶抗體
xy-7040R    Kidins220220kDa蛋白激酶D相互作用蛋白抗體
xy-7041R    phospho-Kidins220 (Ser918)磷酸化220kDa蛋白激酶D相互作用蛋白抗體
xy-4642R    KRV-VP1 + KRV-VP2 (C-terminus)基爾曼氏細(xì)小病毒VP1/VP2抗體(大鼠潛在病毒KRV)C端
xy-6760R    KCNQ1鉀離子通道蛋白家族KCNQ1抗體
xy-5708R    KMT1A組蛋白H3 K9甲基轉(zhuǎn)移酶抗體
xy-6346R    KAT13D生物鐘KAT13D蛋白抗體
xy-9628R    KLHL36Kelch樣蛋白36抗體
xy-12170R    KCC4鉀氯離子轉(zhuǎn)運(yùn)蛋白KCC4抗體
xy-12171R    phospho-KCNA3(Tyr135)磷酸化離子通道蛋白Kv1.3抗體
xy-12172R    KCNE4鉀離子通道蛋白家族成員4抗體
xy-12173R    KCNF1電壓門控性鉀通道蛋白亞基kv5.1抗體
xy-12174R    KCNG1電壓門控性鉀通道蛋白亞基kv6.1抗體
xy-12175R    KCNG3電壓門控性鉀通道蛋白亞基KV6.3抗體