細胞膜鐵轉運蛋白FP1抗體

英文名稱 SLC40A1
中文名稱 細胞膜鐵轉運蛋白FP1抗體
別    名 Ferroportin 1; Ferroportin-1; FPN1; HFE4; IREG1; Iron regulated transporter 1; Iron-regulated transporter 1; MTP1; S40A1_HUMAN; SLC40A1; Solute carrier family 40 member 1; MST079; MSTP079; MTP1; SLC11A3.
   
說 明 書 0.1ml  0.2ml  
研究領域 腫瘤  免疫學  信號轉導  轉錄調節因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Rabbit, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC40A1/FPN1 (365-405aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.

Function:
May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).

Subunit:
Belongs to the S1LC40A transporter family. 

Subcellular Location:
Cell membrane. Localized to the basolateral membrane of polarized epithelial cells.

Tissue Specificity:
Expressed in placenta, intestine, muscle and spleen. xy-5949R    RNF56環指蛋白56
xy-1567R    RAMP1受體活性修飾蛋白1抗體
xy-13705R    ROBLD3胞內接頭蛋白P14抗體
xy-8480R    RBMX2RNA結合蛋白X-連鎖蛋白2抗體
xy-4984R    Rb2 p130視網膜母細胞瘤相關蛋白p130抗體
xy-3421R    Phospho-A Raf (Tyr301 + Tyr302)磷酸化A-Raf抗體
xy-9175R    RNF10環指蛋白10抗體
xy-9323R    RanBP2RAN結合蛋白2/核孔蛋白抗體
xy-9176R    RNF11環指蛋白11抗體
xy-7008R    RPLP2酸性核糖體磷蛋白P2抗體
xy-6809R    RCAS1腫瘤相關表面抗原RCAS1抗體
xy-6305R    Ryanodine Receptor心肌蘭尼堿受體抗體（腦肌蘭尼堿受體）
xy-11168R    RASSF5RASSF5抗體
xy-9157R    RNF93環指蛋白93抗體
xy-9247R    RNF111環指蛋白111抗體
xy-9255R    RNF121環指蛋白121抗體
xy-9259R    RNF169環指蛋白169抗體
xy-9248R    RNF113A環指蛋白113A抗體
xy-7007R    RNF43環指蛋白43抗體
xy-7006R    RASD2腫瘤血管內皮標記蛋白2抗體
xy-9159R    RNF14環指蛋白14抗體
xy-5816R    RRAGARAS相關GTP結合蛋白A抗體
xy-5805R    RIPK-1絲氨酸蘇氨酸激酶1受體相互作用蛋白抗體
xy-5815R    RAIDDCASP2凋亡相關蛋白抗體
xy-5940R    RAD54BDNA修復和重組蛋白RAD54B抗體
xy-5941R    RRAS2畸胎瘤癌基因RAS相關病毒抗體
xy-5954R    RASA3Ras-GTP酶激活蛋白3抗體
xy-11798R    Reticulon 1神經內分泌特異性蛋白抗體
xy-6214R    RDH11視黃醇脫氫酶11/丙型肝炎病毒核心蛋白抗體
xy-6216R    ROR beta維甲酸相關孤兒受體β抗體
xy-6155R    RAP1GDS1G蛋白GTP-GDP解離刺激因子1抗體