類固醇5α還原酶1抗體(5α-Reductase 1)

英文名稱 SRD5A1
中文名稱 類固醇5α還原酶1抗體(5α-Reductase 1)
別    名 3-oxo-5-alpha-steroid 4-dehydrogenase 1; SR type 1; Steroid 5-alpha-reductase 1; S5AR 1; S5A1_HUMAN.
類固醇5α還原酶1抗體(5α-Reductase 1)   
說 明 書 0.1ml  0.2ml  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  轉錄調節因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Horse, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
細胞定位 細胞漿 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SRD5A1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
類固醇5α還原酶1抗體(5α-Reductase 1)
PubMed PubMed
產品介紹 background:
Steroid 5a-Reductase is an important enzyme in androgen physiology because it catalyzes the conversion of testosterone into the more potent 5a-dihydro-testosterone, which mediates androgen effects on target tissues. The enzyme exists as two isoforms: type 1, which is expressed mainly in the skin; and type 2, which is expressed mainly in the prostate. In cultured human skin cells, 5a-Reductase 1 shows heterogeneity of protein, and has different levels of transcriptional and translational expression. 5a-Reductase 1 is expressed in all portions of the hair follicle, whereas 5a-Reductase 2 is expressed only in mesenchymal portions. In addition, 5a-Reductase 1 is mainly expressed in human breast carcinoma and may play a role in the in situ production and actions of the potent androgen 5a-dihydrotestosterone, including inhibition of cancer cell proliferation in hormone-dependent human breast carcinoma. The 5a-Reductase-3a-hydroxysteroid dehydrogenase complex is present in the human brain, suggesting that the complex may be involved in the synthesis of neuroactive steroids or the catabolism of neurotoxic steroids.類固醇5α還原酶1抗體(5α-Reductase 1)xy-1517R    NeuroD1神經細胞分化因子1抗體
xy-1417R    NFAT2活化T細胞核因子1蛋白抗體
xy-2175R    NMDAR1谷氨酸受體1抗體
xy-2590R    NRSF/REST神經元抑制蛋白抗體
xy-2304R    ARHGAP17神經細胞發育相關調控蛋白抗體
xy-1287R    IKB alpha核因子κB抑制蛋白α抗體(IκB-α)
xy-3543R    Phospho-NFKB p65(Ser276)磷酸化細胞核因子NF-κB p65抗體
xy-3544R    Phospho-NFKB1(Ser932)磷酸化細胞核因子p50/k基因結合核因子抗體
xy-3447R    Phospho-eNOS (Ser1177)磷酸化一氧化氮合成酶3（內皮型）抗體
xy-7917R    NUCKS1核酪蛋白激酶和細胞周期蛋白依賴性激酶底物1抗體
xy-7937R    NIFKNIFK蛋白抗體
xy-7938R    phospho-NIFK (Thr234)磷酸化NIFK抗體
xy-8377R    NFX1核轉錄因子X盒結合蛋白1抗體
xy-7763R    NIR2膜磷脂轉移蛋白1抗體
xy-12002R    Neurotensin Receptor 1神經降壓素受體1抗體
xy-12004R    Neurotensin Receptor 2神經降壓素受體2抗體
xy-11988R    Neurabin 1神經組織特異性F肌動蛋白結合蛋白抗體
xy-11976R    NOTCH1胞內活化的Notch1蛋白抗體
xy-11977R    NCS1神經鈣傳感蛋白1抗體
xy-11978R    NECAB1神經元鈣結合相關蛋白EFCBP1抗體
xy-11974R    NUMBL膜相關蛋白樣蛋白NUMBL抗體
xy-11684R    NPEPPS嘌呤霉素敏感性氨肽酶蛋白抗體
xy-11255R    NSFN-乙基順丁烯二酰亞胺敏感融合蛋白抗體
xy-11096R    NIPAL2NIPAL2蛋白抗體
xy-11082R    Neurotrimin神經營養因子HNT抗體
xy-11466R    Neurexin 1 beta軸突蛋白1β/Neurexin 1β抗體
xy-12100R    NMDAR3A谷氨酸受體3A抗體
xy-12102R    NR3B谷氨酸受體3B抗體
xy-12103R    NMDAR3A + 3B谷氨酸受體3A+3B抗體
xy-7617R    NME6P53誘導細胞凋亡抑制蛋白α抗體
xy-7060R    NT5C1A胞質5'核苷酸酶1A抗體