5-羥色胺受體6抗體

英文名稱 5HT6 Receptor
中文名稱 5-羥色胺受體6抗體
別    名 SR-6; 5 HT 6; 5 HT6; 5 hydroxytryptamine 6 receptor; 5 hydroxytryptamine receptor 6; 5-HT-6; 5-HT6; 5-hydroxytryptamine receptor 6; 5HT 6; 5HT6R_HUMAN; HTR 6; HTR6; Serotonin receptor 6.

說 明 書 0.1ml  0.2ml  
研究領域 神經生物學  細胞膜受體  G蛋白偶聯受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Horse, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human 5HT6 Receptor/SR-6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013]

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in several human brain regions, most prominently in the caudate nucleus.xy-3195R    Phospho-IRF3 (Ser396)磷酸化干擾素調節因子3
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xy-3196R    Phospho-IRF7 (Ser471 + Ser472)磷酸化干擾素調節因子7抗體
xy-3198R    phospho-IRS1(Ser302)磷酸化胰島素受體底物-1抗體
xy-3199R    phospho-IRS1(Ser332 + Ser336)磷酸化胰島素受體底物-1抗體
xy-3200R    phospho-IRS1(Ser612)磷酸化胰島素受體底物-1抗體
xy-3203R    phospho-IRS1(Tyr1222)磷酸化胰島素受體底物-1抗體
xy-3204R    phospho-IRS1(Tyr895)磷酸化胰島素受體底物-1抗體
xy-3197R    phospho-IRS1(Ser1101)磷酸化胰島素受體底物-1抗體
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xy-8172R    IKAROS鋅指蛋白IKAROS抗體
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xy-4242R    IP3 receptor5-三磷酸肌醇受體1抗體
xy-4243R    ITPR25-三磷酸肌醇受體2抗體
xy-6229R    ID3DNA結合抑制因子3抗體
xy-4661R    CD275誘導協同刺激分子配體CD275抗體
xy-9202R    IGSF12免疫球蛋白超家族成員12抗體
xy-3946R    IDH3A草酰琥珀酸脫羧酶α抗體
xy-15520R    IFNA5干擾素alpha 5蛋白抗體
xy-4588R    IGF I胰島素樣生長因子1抗體
xy-4880R    IKK betaKB抑制蛋白激酶β抗體
xy-1236R    Involucrin囊包蛋白/內披蛋白抗體
xy-7531R    Insulin Receptor R胰島素受體相關受體抗體
xy-7899R    INCA1INCA1蛋白抗體
xy-9018R    IQCEIQCE蛋白抗體
xy-10050M    IBDV雞傳染性法氏囊病病毒抗體