RSPO1抗體

抗原
R-Spondin 1 (RSPO1)
別名 CRISTIN3, RSPO, RGD1565558, R-spondin, Rspondin
抗原表位
其他選擇 N-Term
N-Term(8),AA 1-263 (5),AA 21-135 (3),AA 136-262 (1),AA 140-263 (1),AA 31-263 (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(39),Rat ((Rattus)) (26),Murine (22)
宿主
其他選擇 Rabbit
Rabbit(35),Mouse (9),Sheep (1)
克隆類型
多克隆
標記
其他選擇 非結合性
Biotin(3),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
應用范圍
其他選擇 Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB)(30),ELISA (26),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (IHC) (9),Immunocytochemistry (ICC) (6),Immunohistochemistry (Frozen Sections) (IHC (fro)) (5),Enzyme Immunoassay (EIA) (1),Immunofluorescence (IF) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1),Neutralization (Neut) (1)
[Pubmed] 1 reference available
規格 0.1 mg
發貨至 中國 (更改)
發貨時間 29至35個工作日

RSPO1抗體

產品細節

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產品細節

顯示 隱藏
免疫原 RSPO1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human RSPO1.
亞型 IgG
特異性 This antibody detects RSPO1. It will not cross-react with RSPO family members.
交叉反應 （詳細） Species reactivity (tested):Human, mouse, rat
純化方法 Peptide affinity chromatography

目標詳細情況

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目標詳細情況

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別名 RSPO1
背景 RSPO1 is a member of a family of secreted growth factors that can operate through the canonical Wnt signaling pathway by stabilizing the intracellular b-catenin, thereby regulating functions mediated by b-catenin such as cell fate decisions and embryonic patterning. RSPO1 was recently identified through linkage analysis to be involved in sex determination and mammalian ovarian development. RSPO1 is thought to regulate cellular responsiveness to Wnt ligands by modulating the cell-surface expression of the Wnt co-receptor LRP6 by interfering with the DKK/Kremen-mediated internalization of LRP6 through an interaction with Kremen, resulting in increased LRP6 cell-surface levels. At least two isoforms of RSPO1 are known to exist.Synonyms: R-spondin-1, Roof plate-specific spondin-1
基因ID 284654
NCBI Accession NP_001033722
UniProt Q2MKA7
研究領域 Reproduction, Wnt, Wnt Signaling

使用細節

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使用細節

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應用備注 ELISA. Western blot: 1 - 2?μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS containing 0.02?% sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Avoid repeated freezing and thawing.
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