RIPK3抗體 

抗原
Receptor-Interacting serine-threonine Kinase 3 (RIPK3)
別名 RIPK3, RIP3, 2610528K09Rik, AW107945, Rip3, Hcyp2
抗原表位
其他選擇 AA 473-486
C-Term(15),N-Term (13),Internal Region (9),AA 479-509 (7),AA 473-486 (4),AA 480-530 (2),AA 61-91 (2),Middle Region (2),AA 1-266 (1),AA 16-239 (1),AA 400-450 (1),AA 455-518 (1),AA 480-518 (1),AA 498-518 (1),AA 50-272 (1),AA 8-38 (1),Center (1)
適用
其他選擇 Murine, Rat ((Rattus))
Human(77),Murine (32),Rat ((Rattus)) (18),Bovine (15),Dog (Canine) (14),Guinea Pig (12),Pig (Porcine) (12),Monkey (2)
宿主
其他選擇 Rabbit
Rabbit(90),Mouse (5)
克隆類型
多克隆
標記
其他選擇 非結合性
Biotin(6),FITC (6),HRP (5),APC (4),Alkaline Phosphatase (AP) (4),PE (4),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應用范圍
其他選擇 Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB)(80),ELISA (39),Immunohistochemistry (IHC) (36),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (19),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Frozen Sections) (IHC (fro)) (4),Enzyme Immunoassay (EIA) (3),Immunocytochemistry (ICC) (3),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (3),Immunoprecipitation (IP) (2),Immunofluorescence (IF) (1)
[Pubmed] 3 references available
規格 0.1 mg
發貨至 中國 (更改)
發貨時間 29至35個工作日

RIPK3抗體 

產品細節

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產品細節

顯示 隱藏
免疫原 RIP3 antibody was raised against a peptide corresponding to amino acids 473 to 486 of Murine RIP3.
亞型 IgG
特異性 This antibody detects RIP3.
交叉反應 （詳細） Species reactivity (tested):Mouse, Rat.
純化方法 Peptide Affinity Chromatography

目標詳細情況

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目標詳細情況

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別名 RIPK3 / RIP3
背景 Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3 (1-3). RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-kB activation. Overexpression of RIP3 induces apoptosis and NF-kappaB activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues (2,3).Synonyms: RIP-3, RIP-like protein kinase 3, Receptor-interacting protein 3, Receptor-interacting serine/threonine-protein kinase 3
分子量 57 kDa
基因ID 56532
UniProt Q9QZL0

 使用細節

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使用細節

顯示 隱藏
應用備注 ELISA. Western blot: 0.5 to 1?μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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貯存及處理

顯示 隱藏
濃度 1.0 mg/mL
緩沖液 PBS, 0.02?% Sodium Azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Avoid repeated freezing and thawing.
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