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CERS6抗體
抗原
Ceramide Synthase 6 (CERS6)
別名 si:ch211-278b7.1, CERS6, CERS5, LASS6, 4732462C07Rik, AW544719, Lass6, T1L, RGD1561599
抗原表位
其他選擇 N-Term
N-Term(10),AA 62-132 (8),C-Term (8),AA 334-361 (7),AA 62-131 (3),AA 335-361 (2)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(49),Rat ((Rattus)) (22),Murine (21),Chicken (12),Bovine (12),Dog (Canine) (12),Pig (Porcine) (12)
宿主
其他選擇 Rabbit
Rabbit(37),Mouse (12)
克隆類型
多克隆
標記
其他選擇 非結合性
Biotin(3),FITC (3),HRP (3),APC (2),Alkaline Phosphatase (AP) (2),PE (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應用范圍
其他選擇 Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB)(40),ELISA (24),Immunohistochemistry (IHC) (12),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6)
[Pubmed] 1 reference available
規格 0.1 mg
發貨至 中國 (更改)
發貨時間 29至35個工作日
CERS6抗體
產品細節
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產品細節
顯示 隱藏
免疫原 LASS6 antibody was raised against a 13 amino acid peptide near the amino terminus of the human LASS6.
亞型 IgG
特異性 This antibody detects LASS6. It is predicted not to cross-react with LASS5.
交叉反應 (詳細) Species reactivity (tested):Human, mouse, rat
純化方法 Peptide affinity chromatography
目標詳細情況
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目標詳細情況
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別名 LASS6
背景 The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development. At least two isoforms of LASS6 are known to exist.Synonyms: LAG1 longevity assurance homolog 6
基因ID 253782
NCBI Accession NP_982288
UniProt Q6ZMG9
研究領域 Cancer, Metabolism
使用細節
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使用細節
顯示 隱藏
應用備注 ELISA. Western blot: 1 - 2?μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only
貯存及處理
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貯存及處理
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緩沖液 PBS containing 0.02?% sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Avoid repeated freezing and thawing.
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