MAP2K2抗體

抗原
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
別名 Prkmk2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2, AA589381, MK2, ATMKK2, F27B13.50, F27B13_50, MAP KINASE KINASE 1, MAP kinase kinase 2, MK1
抗原表位
其他選擇 pSer226
pThr394(41),N-Term (15),pSer226 (11),C-Term (9),Internal Region (8),AA 35-63 (7),Ser222 (7),pSer222 (6),AA 1-400 (5),Thr394 (4),AA 392-396 (3),AA 1-360 (2),AA 1-50 (2),AA 262-292 (2),AA 1-231 (1),AA 1-30 (1),AA 18-234 (1),AA 188-396 (1),AA 2-20 (1),AA 200-229 (1),AA 261-310 (1),AA 291-400 (1),AA 350-400 (1),AA 359-372 (1),AA 44-313 (1),AA 68-204 (1),Arg388 (1),Center (1),Middle Region (1),Ser218 (1),Thr38 (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(181),Murine (94),Rat ((Rattus)) (85),Chicken (13),Dog (Canine) (3),Bovine (2),Rat (Meriones) (1)
宿主
其他選擇 Rabbit
Rabbit(152),Mouse (30),Goat (1),Sheep (1)
克隆類型
多克隆
標(biāo)記
其他選擇 Alexa Fluor 350
Biotin(6),FITC (6),HRP (6),APC (3),Alexa Fluor 488 (3),Alexa Fluor 555 (3),Alexa Fluor 647 (3),Alkaline Phosphatase (AP) (3),Cy3 (3),Cy5 (3),Cy5.5 (3),Cy7 (3),PE (3),Alexa Fluor 350 (2)
應(yīng)用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Western Blotting (WB)(145),Immunohistochemistry (IHC) (60),ELISA (56),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (38),Immunofluorescence (IF) (34),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (29),Immunoprecipitation (IP) (25),Flow Cytometry (FACS) (13),Immunocytochemistry (ICC) (10),Dot Blot (DB) (8),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (8),Enzyme Immunoassay (EIA) (4),Immunoassay (IA) (4),Fluorescence Microscopy (FM) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
規(guī)格 100 μL
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MAP2K2抗體

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產(chǎn)品細(xì)節(jié)

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免疫原 KLH conjugated synthetic phosphopeptide derived from human MEK2 around the phosphorylation site of pSer226
亞型 IgG
特異性 Excitation / Emission Wavelengths: 343nm/442nm
交叉反應(yīng) Rat ((Rattus))
純化方法 purified by Protein A

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目標(biāo)詳細(xì)情況

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別名 MEK2
背景 The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].
分子量 46kDa
基因ID 5605

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應(yīng)用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說明

Excitation / Emission wavelength: 343nm / 442nm

限制 For Research Use only

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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