FANCD2 抗體

抗原
Fanconi Anemia, Complementation Group D2 (FANCD2)
別名 FANCD2, CG17269, CG31192, CG31194, DmelCG17269, dmFANCD2, xfancd2, FA-D2, FA4, FACD, FAD, FAD2, FANCD, 2410150O07Rik, AU015151, BB137857
抗原表位
其他選擇 pSer222
pSer222(23),pSer1404 (13),N-Term (10),Ser222 (5),C-Term (4),AA 1401-1451 (2),Isoform B (2),AA 1-49 (1),AA 188-237 (1),AA 351-400 (1),Internal Region (1),Middle Region (1),Pro216 (1),Ser371 (1),ubiquitinated (1)
適用
其他選擇 Human, Murine, Rat ((Rattus)), Dog (Canine), Pig (Porcine), Bovine
Human(102),Murine (56),Rat ((Rattus)) (46),Bovine (35),Dog (Canine) (23),Pig (Porcine) (23),Zebrafish (6)
宿主
其他選擇 Rabbit
Rabbit(97),Mouse (14)
克隆類型
多克隆
標記
其他選擇 Alexa Fluor 555
Biotin(4),HRP (4),Alexa Fluor 350 (3),Alexa Fluor 488 (3),Alexa Fluor 647 (3),Cy3 (3),Cy5 (3),Cy5.5 (3),Cy7 (3),FITC (3),Alexa Fluor 555 (2),DyLight 488 (1),DyLight 550 (1),DyLight 650 (1)
應用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Western Blotting (WB)(73),Immunohistochemistry (IHC) (40),ELISA (31),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (29),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (24),Immunoprecipitation (IP) (17),Immunofluorescence (IF) (13),Flow Cytometry (FACS) (10),Immunocytochemistry (ICC) (3),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (3),Enzyme Immunoassay (EIA) (1),Immunoassay (IA) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1),Proximity Ligation Assay (PLA) (1)
規格 100 μL
發貨至 中國 (更改)

FANCD2 抗體

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產品細節

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免疫原 KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of pSer222
亞型 IgG
特異性 Excitation / Emission Wavelengths: 553nm/568nm
交叉反應 Rat ((Rattus)), Dog (Canine), Pig (Porcine), Bovine
純化方法 purified by Protein A

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目標詳細情況

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別名 FANCD2
背景 Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
分子量 166kDa
基因ID 2177

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應用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說明

Excitation / Emission wavelength: 553nm / 568nm

限制 For Research Use only

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狀態 Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C

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