EIF4E抗體

抗原
Eukaryotic Translation Initiation Factor 4E (EIF4E)
別名
0260/09, 0587/11, 0589/11, 0919/12, 1004/13, 2, 7238, CBP, CG4035, CT13384, CT39424, CT39426, D-eIF4E, DmelCG4035, Eif4E, Eif4e, IF4E, dEif4e, deIF-4E, deIF4E, eIF 4E, eIF-4E1, eIF-4E2, eIF-4EII, eI ... show more
0260/09, 0587/11, 0589/11, 0919/12, 1004/13, 2, 7238, CBP, CG4035, CT13384, CT39424, CT39426, D-eIF4E, DmelCG4035, Eif4E, Eif4e, IF4E, dEif4e, deIF-4E, deIF4E, eIF 4E, eIF-4E1, eIF-4E2, eIF-4EII, eIF-4e, eIF4E, eIF4E-1, eIF4E-1/2, eIF4E-2, eIF4E1, eIF4EI, eIF4e, eif-4E, eif-4e, eif4e, l(3)07238, l(3)67Af, l(3)S025007, l(3)S026009, l(3)S058711, l(3)S091912, eIF-4E, cbp, eif4f, eif4e1, eif4el1, AUTS19, EIF4E1, EIF4EL1, EIF4F, EG668879, Eif4e-ps, If4e, EIF-4E, eif4e-1, zgc:86680 show less
抗原表位
其他選擇 pSer209
pSer209(55),N-Term (14),Ser209 (14),C-Term (9),AA 1-217 (3),AA 167-217 (2),AA 207-211 (2),AA 32-61 (2),AA 1-144 (1),AA 1-50 (1),AA 168-217 (1),AA 2-217 (1),Arg215 (1),Ser1232 (1),Ser328 (1),Thr203 (1)
適用
其他選擇 Human, Murine, Rat ((Rattus)), Chicken, Dog (Canine), Pig (Porcine), Bovine
Human(194),Rat ((Rattus)) (89),Murine (84),Chicken (24),Bovine (24),Dog (Canine) (23),Pig (Porcine) (23),Monkey (2),Rabbit (2),Zebrafish (Danio rerio) (2),Xenopus laevis (1)
宿主
其他選擇 Rabbit
Rabbit(155),Mouse (41)
克隆類型
多克隆
標記
其他選擇 Alexa Fluor 350
Biotin(7),FITC (7),HRP (7),APC (4),Alkaline Phosphatase (AP) (4),PE (4),Alexa Fluor 488 (3),Alexa Fluor 555 (3),Alexa Fluor 647 (3),Cy3 (3),Cy5 (3),Cy5.5 (3),Cy7 (3),Alexa Fluor 350 (2)
應(yīng)用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Western Blotting (WB)(156),Immunohistochemistry (IHC) (86),ELISA (58),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (38),Flow Cytometry (FACS) (36),Immunofluorescence (IF) (31),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (29),Immunocytochemistry (ICC) (14),Dot Blot (DB) (11),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (11),Immunoprecipitation (IP) (9),Enzyme Immunoassay (EIA) (4),Fluorescence Microscopy (FM) (1),Immunoassay (IA) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
規(guī)格 100 μL
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EIF4E抗體

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產(chǎn)品細節(jié)

顯示 隱藏
免疫原 KLH conjugated synthetic phosphopeptide derived from human eIF4E around the phosphorylation site of pSer209 ,[SG(p-S)TT]
亞型 IgG
特異性 Excitation / Emission Wavelengths: 343nm/442nm
交叉反應(yīng) Rat ((Rattus)), Chicken, Dog (Canine), Pig (Porcine), Bovine
純化方法 purified by Protein A

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別名 eIF4E
背景 EIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.
分子量 24kDa
基因ID 1977

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應(yīng)用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說明

Excitation / Emission wavelength: 343nm / 442nm

限制 For Research Use only

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C

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