MILR1抗體

抗原
Mast Cell Immunoglobulin-Like Receptor 1 (MILR1)
別名 Allergin-1, Gm885, Mca32, C17orf60, MCA-32, MCA32
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(14),Murine (11),Rat ((Rattus)) (11)
宿主
其他選擇 Rabbit
Rabbit(13),Sheep (1)
克隆類型
多克隆
標記
其他選擇 Cy5.5
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy7 (1),FITC (1),HRP (1)
應用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Immunofluorescence (Paraffin-embedded Sections) (IF (p))(9),Western Blotting (WB) (6),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3)
規格 100 μL
發貨至 中國 (更改)

MILR1抗體

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產品細節

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免疫原 KLH conjugated synthetic peptide derived from human Allergin-1
亞型 IgG
交叉反應 Murine, Rat ((Rattus))
純化方法 purified by Protein A

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目標詳細情況

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別名 Allergin-1
背景 As a major event in type ? allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (Fc?RIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to Fc?RIs on mast cells may inhibit the signal transduction from Fc?RIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.

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應用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說明

Excitation / Emission wavelength: 675nm / 694nm

限制 For Research Use only

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狀態 Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲存液 Sodium azide
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儲存條件 4 °C