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AFAP1L2 抗體
抗原
Actin Filament Associated Protein 1-Like 2 (AFAP1L2)
別名 KIAA1914, XB130, AU041783, C86904, mKIAA1914, RGD1310668
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(32),Murine (24),Rat ((Rattus)) (24)
宿主
其他選擇 Rabbit
Rabbit(32)
克隆類型
多克隆
標記
其他選擇 Cy5.5
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy7 (1),FITC (1),HRP (1)
應用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Western Blotting (WB)(24),ELISA (13),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (9),Immunohistochemistry (IHC) (9),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8),Enzyme Immunoassay (EIA) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2),Flow Cytometry (FACS) (1)
規格 100 μL
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AFAP1L2 抗體
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產品細節
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免疫原 KLH conjugated synthetic peptide derived from human AFAP1L2
亞型 IgG
交叉反應 Murine, Rat ((Rattus))
純化方法 purified by Protein A
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別名 AFAP1L2
背景 Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.
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應用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說明
Excitation / Emission wavelength: 675nm / 694nm
限制 For Research Use only
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狀態 Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C
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