STAT1抗體

抗原
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1)
別名 IMUP, H2RSP, IMUP-1, IMUP-2, 2010005J02Rik, AA408197, DD6G4-4, CANDF7, ISGF-3, STAT91, STAT4, XStat1, STAT, STAT1, dZ182H3.3, si:by134g18.2, si:by51f19.1, si:dz182h3.3, si:dz199m19.1, si:dz73o4.2
抗原表位
其他選擇 N-Term
pTyr701(56),pSer727 (55),C-Term (47),Ser727 (15),AA 613-712 (9),AA 717-745 (9),N-Term (9),AA 1-712 (6),Internal Region (5),Tyr701 (5),AA 721-733 (4),Transcript Variant Beta (4),AA 699-703 (3),AA 725-729 (3),AA 8-23 (3),Middle Region (2),AA 175-225 (1),AA 233-524 (1),AA 343-602 (1),AA 423-690 (1),AA 432-680 (1),AA 51-235 (1),AA 519-712 (1),AA 579-750 (1),AA 668-717 (1),AA 680-730 (1),AA 686-750 (1),AA 694-743 (1),AA 700-750 (1),AA 711-730 (1),AA 712-750 (1),Asp733 (1),Gly695 (1),Leu177 (1),Tyr1214 (1),Tyr1217 (1),alpha beta (1),non-phosphorylated (1),pThr1 (1),phosphorylated (1)
適用
其他選擇 Murine, Rat ((Rattus)), Dog (Canine), Pig (Porcine), Xenopus laevis, Zebrafish (Danio rerio), Bovine, Human, Chicken
Human(335),Murine (165),Rat ((Rattus)) (151),Dog (Canine) (42),Bovine (40),Pig (Porcine) (28),Chicken (26),Monkey (4),Rat (Meriones) (1),Xenopus laevis (1)
宿主
其他選擇 Rabbit
Rabbit(281),Mouse (67),Chicken (4),Hamster (4),Goat (3)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(7),FITC (6),HRP (6),Alexa Fluor 488 (4),APC (3),Alexa Fluor 350 (3),Alexa Fluor 555 (3),Alexa Fluor 647 (3),Alkaline Phosphatase (AP) (3),Cy3 (3),Cy5 (3),Cy5.5 (3),Cy7 (3),PE (3),Magnetic Particles (1),Sepharose (1)
應(yīng)用范圍
其他選擇 Immunohistochemistry (IHC), Western Blotting (WB)
Western Blotting (WB)(316),Immunohistochemistry (IHC) (114),ELISA (111),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (74),Immunoprecipitation (IP) (73),Immunofluorescence (IF) (37),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (30),Immunocytochemistry (ICC) (28),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (20),Enzyme Immunoassay (EIA) (10),Flow Cytometry (FACS) (6),Immunohistochemistry (Frozen Sections) (IHC (fro)) (6),Dot Blot (DB) (4),Immunoassay (IA) (4),Activation (Act) (1),Proximity Ligation Assay (PLA) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日

STAT1抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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免疫原 Synthetic peptide directed towards the N terminal of human STAT1
序列 MSQWYELL DSKFLEQVHQ LYDDSFPMEI RQYLAQWLEK QDWEHAANDV
預(yù)測反應(yīng) Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, African clawed frog : 90 %, Bovine : 80 %, Sheep : 80 %, Zebrafish : 80 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against STAT1. It was validated on Western Blot and immunohistochemistry.
純化方法 Affinity Purified

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 STAT1
背景 STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
分子量 87 kDa
基因ID 6772
NCBI Accession NP_009330, NM_007315
UniProt P42224
研究領(lǐng)域 Cancer, Transcription Factors, Signaling, Receptors, Inflammation

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使用細(xì)節(jié)

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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 750 AA

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
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