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HSPA5抗體

參   考   價(jià): 1800

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HSPA5抗體 的概念:
Z初有人用電泳證明血清中抗體活性在γ球蛋白部分,故曾把抗體統(tǒng)稱為丙種(γ)球蛋白。后來(lái)發(fā)現(xiàn),抗體并不都在γ區(qū);并且位于γ區(qū)的球蛋白,也不一定都具有抗體活性,規(guī)格:0.1ml/100µg、0.2ml/200µg

HSPA5抗體 

抗原
Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5)
別名
GRP78, BiP, GRP-78, grp78, hspa5a, BIP, MIF2, AL022860, AU019543, Bip, D2Wsu141e, D2Wsu17e, Grp78, Hsce70, SEZ-7, Sez7, baffled, mBiP, cb865, fb60h09, fi36d04, wu:fb60h09, wu:fi36d04, zgc:55994, zgc:7 ... show more
GRP78, BiP, GRP-78, grp78, hspa5a, BIP, MIF2, AL022860, AU019543, Bip, D2Wsu141e, D2Wsu17e, Grp78, Hsce70, SEZ-7, Sez7, baffled, mBiP, cb865, fb60h09, fi36d04, wu:fb60h09, wu:fi36d04, zgc:55994, zgc:77606 show less
抗原表位
其他選擇 AA 261-289, Center
N-Term(26),C-Term (15),AA 24-43 (4),AA 250-300 (4),AA 270-300 (4),AA 548-587 (4),Internal Region (4),AA 550-600 (3),AA 497-581 (2),AA 541-568 (2),AA 600-654 (2),AA 643-654 (2),AA 645-654 (2),AA 1-654 (1),AA 113-335 (1),AA 17-28 (1),AA 19-654 (1),AA 261-289 (1),AA 340-617 (1),AA 478-654 (1),AA 559 (1),AA 594-655 (1),AA 649-654 (1),Gly584 (1),Pro641 (1)
適用
其他選擇 Human, Zebrafish (Danio rerio)
Human(170),Rat ((Rattus)) (72),Murine (60),Xenopus laevis (7),Bovine (6),Monkey (6),Hamster (5),Rabbit (5),Zebrafish (3),Chicken (2),Cryphonectria parasitica (2),Dog (Canine) (2),Fungi (Ascomycota) (2),Fungus (Cryphonectria parasitica) (2),Mammalian (2),Sheep (Ovine) (2),Fungus (1),Rat (Meriones) (1),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(139),Mouse (61),Rat (4),Sheep (1)
克隆類型 (克隆位點(diǎn))
多克隆 (RB20813)
標(biāo)記
其他選擇 非結(jié)合性
Biotin(9),FITC (7),APC (6),Alkaline Phosphatase (AP) (6),PE (6),Atto 390 (4),Atto 488 (4),Atto 565 (4),Atto 594 (4),Atto 633 (4),Atto 655 (4),Atto 680 (4),Atto 700 (4),HRP (4),PE-Atto 594 (4),PerCP (4),Streptavidin (4),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Western Blotting (WB)(191),ELISA (94),Immunohistochemistry (IHC) (62),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (34),Immunofluorescence (IF) (24),Immunocytochemistry (ICC) (20),Immunofluorescence (Cultured Cells) (IF (cc)) (10),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Flow Cytometry (FACS) (9),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (8),Enzyme Immunoassay (EIA) (6),Functional Studies (Func) (3),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1),Immunoprecipitation (IP) (1)
[Pubmed] 2 references available
規(guī)格 400 μL
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至13個(gè)工作日

HSPA5抗體 

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 This HSPA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 AA from the Central region of human HSPA5.
克隆位點(diǎn) RB20813
亞型 Ig
特異性 This HSPA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the Central region of human HSPA5.
預(yù)測(cè)反應(yīng) Cow (Bovine),Chicken,Mouse (Murine),Rat (Rattus)
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

 目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

顯示 隱藏
別名 HSPA5
背景 When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.
Synonyms: Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Immunoglobulin heavy chain-binding protein, BiP, Heat shock 70 kDa protein 5, 78 kDa glucose-regulated protein, GRP-78,GRP78, HSPA5
分子量 72333 DA
基因ID 3309
UniProt P11021
研究領(lǐng)域 Signaling, Phospho-specific antibodies, Cell Signaling, Stem Cells, Protein Modifications, Chromatin, Cell Structure

 使用細(xì)節(jié)

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使用細(xì)節(jié)

顯示 隱藏
應(yīng)用備注 WB = 1:1000, IHC = 1:50-100, IF = 1:10-50
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 0.5 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C/-20 °C
儲(chǔ)存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months

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