STIM1 抗體

抗原
Stromal Interaction Molecule 1 (STIM1)
別名 stim1, MGC76045, STIM1, si:dkey-24p1.5, MGC154748, si:ch211-112l17.2, Stim1, D11S4896E, GOK, TAM, SIM
抗原表位
其他選擇 Middle Region
C-Term(28),AA 24-686 (9),AA 600-685 (8),AA 516-546 (6),AA 1-213 (4),Extracellular Domain (4),AA 24-685 (3),Internal Region (3),AA 50-100 (2),AA 509-538 (2),Cytoplasmic Domain (2),N-Term (2),AA 1-685 (1),AA 428-685 (1),AA 550-600 (1),AA 6-368 (1),AA 635-685 (1),Middle Region (1)
適用
其他選擇 Human
Human(84),Murine (41),Rat ((Rattus)) (41),Dog (Canine) (20),Bovine (19),Pig (Porcine) (13),Chicken (12),Zebrafish (2)
宿主
其他選擇 Rabbit
Rabbit(61),Mouse (22),Goat (3),Sheep (1)
克隆類型
多克隆
標記
其他選擇 非結合性
Biotin(3),FITC (3),HRP (3),APC (2),Alkaline Phosphatase (AP) (2),PE (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),DyLight 488 (1),DyLight 550 (1),DyLight 650 (1)
應用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(73),ELISA (33),Immunohistochemistry (IHC) (27),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (25),Immunoprecipitation (IP) (11),Immunocytochemistry (ICC) (10),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunofluorescence (IF) (8),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (5),Enzyme Immunoassay (EIA) (4),Immunoassay (IA) (1)
規格 50 μg
發貨至 中國 (更改)
發貨時間 9至12個工作日

STIM1 抗體

產品細節

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產品細節

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免疫原 Synthetic peptide directed towards the middle region of human STIM1
序列 LDSSRSHSPS SPDPDTPSPV GDSRALQASR NTRIPHLAGK KAVAEEDNGS
預測反應 Human : 100 %, Mouse : 100 %, Rat : 100 %, Horse : 90 %, Bovine : 80 %, Dog : 80 %
產品特性 This is a rabbit polyclonal antibody against STIM1. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標詳細情況

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別名 STIM1
背景 This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.
分子量 75 kDa
基因ID 6786
NCBI Accession NM_003156, NP_003147
UniProt Q13586

使用細節

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應用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 685 AA

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態 Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項 Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
儲存方法 For longer periods of storage, store at -20 °C

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