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Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) 抗體
抗原
Autophagy/beclin-1 Regulator 1 (AMBRA1)
別名 2310079H06Rik, A130023A14, AA474864, AV021921, D030051N19Rik, mKIAA1736, Nyw1, DCAF3, WDR94
抗原表位
其他選擇 N-Term
N-Term(22),C-Term (14),AA 1-50 (2),AA 27-55 (2),AA 1200-1250 (1),AA 14-239 (1),AA 807-1092 (1),Internal Region (1)
適用
其他選擇 Human, Murine
Human(59),Murine (47),Rat ((Rattus)) (31),Chicken (13),Dog (Canine) (12),Bovine (1)
宿主
其他選擇 Rabbit
Rabbit(66),Mouse (1)
克隆類型
多克隆
標記
其他選擇 非結合性
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
應用范圍
其他選擇 ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Western Blotting (WB)(56),Immunohistochemistry (IHC) (29),ELISA (27),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (14),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunoprecipitation (IP) (7),Enzyme Immunoassay (EIA) (4),Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (4),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (3),Immunoassay (IA) (1),Immunofluorescence (IF) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
規格 0.1 mg
發貨至 中國 (更改)
發貨時間 24至29個工作日
Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) 抗體
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產品細節
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免疫原 The immunogen for anti-Ambra1 antibody: antibody was raised against a 18 amino acid peptide from near the amino terminus of human Ambra1.
預測反應 Human Mouse
產品特性 Autophagy, The Process Of Bulk Degradation Of Cellular Proteins Through An Autophagosomic-Lysosomal Pathway Is Important For Normal Growth Control And May Be Defective In Tumor Cells. It Is Involved In The Preservation Of Cellular Nutrients Under Starvation Conditions As Well As The Normal Turnover Of Cytosolic Components. Beclin-1, A Principal Regulator Of Autophagosome Formation, Is In Turn Regulated By Ambra1. Ambra1 Associates With Beclin-1 Through A Region Near Its Center As Determined By Yeast Two-Hybrid Assay. Null Mutations In This Gene In Mice Resulted In Embryonic Lethality With Severe Neural Tube Defects Associated With Autophagy Impairment, Accumulation Of Ubiquitinated Proteins, Unbalanced Cell Proliferation And Excessive Apoptotic Death . Furthermore, Down-Regulation Of Ambra1 In Cultured Cells Though Rna Interference Decreased The Level Of Rapamycin- And Nutrient Starvation-Induced Autophagy. Multiple Isoforms Of Ambra1 Are Known To Exist.
純化方法 Affinity chromatography purified via peptide column
Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) 抗體目標詳細情況
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目標詳細情況
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別名 Ambra1
背景 (NT) Autophagy Regulating Protein
使用細節
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Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) 抗體使用細節
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應用備注 Ambra1 antibody can be used for the detection of Ambra1 by Western blot at 2 - 4?μg/mL
限制 For Research Use only
貯存及處理
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貯存及處理
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注意事項 As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
儲存條件 4 °C
儲存方法 Ambra1 antibody can be stored at 4 °C
有效期 12 months
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