Actin Filament Associated Protein 1-Like 2 (AFAP1L2) (C-Term) 抗體

抗原
Actin Filament Associated Protein 1-Like 2 (AFAP1L2)
別名 KIAA1914, XB130, AU041783, C86904, mKIAA1914, RGD1310668
抗原表位
其他選擇 C-Term
C-Term(10),N-Term (3),AA 1-241 (1),AA 554-818 (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(32),Murine (24),Rat ((Rattus)) (24)
宿主
其他選擇 Rabbit
Rabbit(32)
克隆類型
多克隆
標記
其他選擇 非結合性
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
應用范圍
其他選擇 ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Western Blotting (WB)(23),ELISA (12),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (IHC) (8),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8),Enzyme Immunoassay (EIA) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2),Flow Cytometry (FACS) (1)
規格 0.1 mg
發貨至 中國 (更改)
發貨時間 24至29個工作日

Actin Filament Associated Protein 1-Like 2 (AFAP1L2) (C-Term) 抗體

產品細節

貯存及處理 使用細節 目標詳細情況 回頁首

產品細節

顯示 隱藏
免疫原 The immunogen for anti-AFAP1L2 antibody: antibody was raised against a 15 amino acid peptide near the carboxy terminus of human AFAP1L2.
預測反應 Human Mouse Rat
產品特性 Afap1l2, Also Known As Xb130, Is Structurally Similar To Actin-Filament-Associated Protein (AFAP), Containing Several Sh2- And Sh3-Binding Motifs, Two Pleckstrin Homology Domains, A Coiled-Coil Region, And Many Potential Phosphorylation Sites. It Interacts With And Is Phosphorylated By C-Src Tyrosine Kinase. Suppression Of Afap1l2 Via Sirna Reduced Src Activity, Il-8 Production, Egf-Induced Phosphorylation Of Akt And Gsk3beta, And Altered Cell Cycles In Human Lung Epithelial Cells Suggesting That Afap1l2 Plays A Role As An Adaptor In The Regulation Of Src Signal Transduction And Multiple Cellular Functions. Recent Experiments Have Shown That Afap1l2 Is Highly Expressed In Thyroid And Is The Substrate Ret/Ptc Kinase, A Thyroid-Specific Kinase That Plays A Pathogenic Role In Papillary Thyroid Cancer. Down-Regulation Of Afap1l2 In These Cancer Cells Reduced Akt Activity, Inhibiting Cell-Cycle Progression And Cancer Cell Survival In Suspension, Indicating That Afap1l2 May Be A Valuable Target In Thyroid Cancer Therapy. At Least Four Isoforms Of Afap1l2 Are Known To Exist.
純化方法 Affinity chromatography purified via peptide column

Actin Filament Associated Protein 1-Like 2 (AFAP1L2) (C-Term) 抗體目標詳細情況

貯存及處理 使用細節 回頁首

目標詳細情況

顯示 隱藏
別名 AFAP1L2
背景 Actin Filament Associated Protein 1-Like 2 Protein

使用細節

貯存及處理 目標詳細情況 回頁首

Actin Filament Associated Protein 1-Like 2 (AFAP1L2) (C-Term) 抗體使用細節

顯示 隱藏
應用備注 AFAP1 L2 antibody can be used for detection of AFAP1 L2 by Western blot at 1 - 2?μg/mL
限制 For Research Use only

貯存及處理

使用細節 目標詳細情況 回頁首

貯存及處理

顯示 隱藏
注意事項 As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
儲存條件 4 °C
儲存方法 AFAP1L2 antibody can be stored at 4 °C
有效期 12 monthsxy-13807R CCDC62卷曲螺旋結構域蛋白62抗體
xy-13808R CCDC64卷曲螺旋結構域蛋白64抗體
xy-13811R CCDC72卷曲螺旋結構域蛋白72抗體
xy-13812R CCDC73卷曲螺旋結構域蛋白73抗體
xy-13813R CCDC74B卷曲螺旋結構域蛋白74B抗體
xy-13782R C19orf2519號染色體開放閱讀框25抗體
xy-13783R C19orf4219號染色體開放閱讀框42抗體
xy-13784R C19orf4419號染色體開放閱讀框44抗體
xy-13785R C19orf4819號染色體開放閱讀框48抗體
xy-13786R C19orf5019號染色體開放閱讀框50抗體
xy-13787R C19orf5119號染色體開放閱讀框51抗體
xy-13788R C19orf5219號染色體開放閱讀框52抗體
xy-13789R C19orf5519號染色體開放閱讀框55抗體
xy-13790R C19orf5619號染色體開放閱讀框56抗體
xy-13791R C19orf5719號染色體開放閱讀框57抗體
xy-13792R C19orf6119號染色體開放閱讀框61抗體
xy-13798R C19orf7719號染色體開放閱讀框77抗體
xy-13800R C1D核DNA結合蛋白C1D抗體
xy-13757R C1orf1581號染色體開放閱讀框58抗體
xy-13758R C21orf6621號染色體開放閱讀框66抗體
xy-13759R CDC42EP3CDC42效應蛋白3抗體
xy-15268R C7orf 437號染色體開放閱讀框43抗體
xy-10351R phospho-c-ABL (Tyr115)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10356R phospho-c-Abl (Thr754 + Thr735) 磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10355R phospho-c-ABL (Tyr245)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10354R phospho-c-ABL(Thr413) 磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10353R phospho-c-ABL(Tyr204)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10352R phospho-c-ABL (Thr754)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10309R Cenexin1精子尾部結構蛋白抗體