英文名稱 COX7A2
中文名稱 細胞色素c氧化酶COX7A2抗體
別    名 Mitochondrion. Cytochrome c oxidase subunit 7A2, mitochondrial; COX7a related protein; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-liver/heart; COX7a-related protein; COX7AR; COX7RP; Cytochrome c oxidase subunit VIIa related protein, mitochondrial; Cytochrome c oxidase subunit VIIaL; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-related protein, mitochondrial [Precursor]; EB1; Estrogen receptor binding CpG island; SIG81; CX7A2_HUMAN.
細胞色素c氧化酶COX7A2抗體  
說 明 書 0.1ml  0.2ml  
研究領域 信號轉導  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 6.7kDa
細胞定位 細胞漿 細胞膜 線粒體
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human COX7A2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq]

Function:
May be a regulatory subunit of cytochrome c oxidase that mediates the higher level of energy production in target cells by estrogen.

Subcellular Location:
Mitochondrion inner membrane.

Similarity:
Belongs to the cytochrome c oxidase VIIa family.

Gene ID:
1347

Database links:

Entrez Gene: 1347 Human

Entrez Gene: 12866 Mouse

Entrez Gene: 29507 Rat

Omim: 123996 Human

SwissProt: P14406 Human

SwissProt: P48771 Mouse

SwissProt: P35171 Rat

Unigene: 70312 Human

Unigene: 152627 Mouse

Unigene: 1745 Rat

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