英文名稱 LILRB3/CD85a
中文名稱 白細胞免疫球蛋白樣受體-B抗體
別    名 CD85 antigen like family member A; CD85a; CD85a antigen; HL9; IL T5; ILT5; Immunoglobulin like transcript 5; Leukocyte immunoglobulin like receptor 3; Leukocyte immunoglobulin like receptor subfamily B (with TM and ITIM domains) member 3; Leukocyte immunoglobulin like receptor subfamily B member 3; LIR 3; LIR3; Gp91; Pirb; MGC138403; Monocyte inhibitory receptor HL9; PIRB; Lilrb3; 16M4; 16M5; 16M6; 6M1; 7M5; PIRB1; PIRB2; PIRB3; PIRB4;PIRB5.
白細胞免疫球蛋白樣受體-B抗體
   
說 明 書 0.1ml  0.2ml  
研究領域 免疫學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human LILRB3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

產品介紹 background:
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
May act as receptor for class I MHC antigens.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Detected in monocytes and B-cells.

Gene ID:
11025

Database links:

Entrez Gene: 11025 Human

Omim: 604820 Human

SwissProt: O75022 Human

Unigene: 631592 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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