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南京科佰生物科技有限公司
主營產品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
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聯系電話
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南京科佰生物科技有限公司
主營產品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
聯系電話
| 參考價 | ￥ 900 |
| 訂貨量 | 1件 |
更新時間：2022-11-25 14:47:19瀏覽次數：400
聯系我們時請說明是化工儀器網上看到的信息，謝謝!
CBP10446 | |
| Gene | APC |
| Description | APC, adenomatous polyposis coli, is a tumor suppressor (PMID: 30562755) and multi-domain protein regulating numerous cellular functions through interaction with beta-catenin and subsequent inhibition of Wnt signalling (PMID: 21502284). APC germline mutations are associated with familial adenomatous polyposis (PMID: 30562755) and somatic mutations with colon, endometrial, NSCLC, and breast cancers (PMID: 27283171). |
| Technical Data | |
| DNA Change | c.4290delC |
| AA Change | p.T1430fs |
| Mutation type | Frame_Shift_Del |
| Zygosity | Heterozygous |
| Allelic Frequency | 66.66% |
| Transcript | ENST00000457016.1 |
| Cosmic ID | COSM19052 |
| Chr position(GRCh37) | chr5:112175581 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
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| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
