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南京科佰生物科技有限公司
主營產品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
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南京科佰生物科技有限公司
主營產品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
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更新時間：2022-05-05 14:22:01瀏覽次數：606
聯系我們時請說明是化工儀器網上看到的信息，謝謝!
| CBP73320 | |
| I. Introduction | |
Cell Line Name： | SDC4-ROS1/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
| SDC4, syndecan 4, is a heparan sulfate proteoglycan that plays a role in intracellular signaling, including cell adhesion and cell-matrix interactions. SDC4 expression has been associated with breast cancer, a SDC4-ROS1 fusion has been identified in NSCLC and a SDC4-NRG1 fusion has been identified in lung adenocarcinoma and squamous cell carcinoma . | |
| III. Representative Data | |
1.Sanger of SDC4-ROS1/BaF3
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2. Anti-proliferation assay
Figure 2. CTG Proliferation Assay of BaF3 SDC4-ROS1 (C1). | |
