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南京科佰生物科技有限公司
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南京科佰生物科技有限公司
主營產品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
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更新時間：2022-08-01 10:14:14瀏覽次數：694
聯系我們時請說明是化工儀器網上看到的信息，謝謝!
| 供貨周期 | 現貨 | 規格 | T-25 Flask |
|---|---|---|---|
| 貨號 | CBP74122 | 應用領域 | 生物產業 |
| 主要用途 | 僅限科研使用 |
| CBP74122 | |
| I. Background | |
SIRP alpha protein, or Signal regulatory proteinalpha (SIRP-α), also known as Tyrosine protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_080792, a.a. 27-370, with C-terminal Avi and His tags, MW 40.3 kDa*. This SIRP alpha protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in higher molecular weight. | |
| II. Introduction | |
| Expressed gene: | SIRPɑ |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Synonym(s): | SIRP alpha protein, sirpa protein, sirp-a protein, SIRP?±, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, 71138-1, 71138-2 |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin+300ug/ml hygromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Representative Data | |
Figure 1. Dose response of Sirpɑ Blocking Antibodies in SIRPɑ Effector Reporter Cells With CD47+ Target Cells.
Figure 2. Dose response of CD47 Blocking Antibody in SIRPɑ Effector Reporter Cells(C11) With CD47+ Target Cells. | |
