動物實驗低壓氧艙用于模擬低壓氧環境，氧氣濃度可自動控制，解決了艙體內氧濃度的自動控制問題，同時氣體濃度在艙體內更均勻，適用于中小型動物如犬、猴、兔、鼠等。

由動物艙體、氣體輸送控制系統、環境監測系統、視頻監測功能、溫控系統等構成。通過調節動物艙內氧氣（或空氣）和氮氣的混合比例，間接控制氧氣濃度的效果；氧氣濃度的大小以及維持低氧環境的時間，均由中央處理器自動控制，設備的自動化程度高，無須專人守候；流量計、分布器以及緩沖罐的使用，減小甚至消除了細股急流氣體對小動物的影響，具有供氣均勻、平緩的優點，從源頭上消除了動物艙氧濃度分布不均勻的現象。

功能及特點

1.確保安全

從設計開始到zui終完成測試和檢查，所有實驗氧艙都遵循嚴格的生產過程；

具有緊急關閉和自動排氣系統，以適應各種情況。

2.動物艙體

ProOx-810 動物實驗低壓氧艙主體采用進口亞克力加厚材質，堅固可靠，透明方便觀察；

鋁合金及不銹鋼材料支撐；

具有腳輪腳剎設計，方便移動。

3.氣體輸送控制系統

醫用級靜音高壓泵及低壓泵，為系統提供穩定的壓力；

4.整體管路采用防爆管，抗壓強；

具有氣體緩沖器，減小甚至消除了細股急流氣體對小動物的影響；

多級空氣過濾器確保空氣來源清潔，消除碳氫化合物可能引起的火災危險；同時去除空氣供應中的微粒物質、水分、油和油蒸氣。

5.自動控制氧濃度及維持氧濃度的持續時間。

實驗監測、控制、報警

監測參數：艙體內溫度、濕度、壓力、氧氣濃度、二氧化碳濃度監測

控制參數：艙體內的溫度、濕度、壓力、氧氣濃度、氧濃度維持時間

報警參數：溫度上限、溫度下限、壓力上限、壓力下限、氧濃度上限、氧濃度下限

6.動物生理指標監測

監測指標（選配）：心電圖、體溫、血壓、呼吸、血氧飽和度

具有擴展接口，用于靜脈注射、采血、血壓監測等

7.視頻監測功能

配備視頻采集卡及攝像頭，可錄像拍照

8.溫控系統

具有動物恒溫平臺，溫度可控制

采用水循環恒溫機制，防止電加熱過程在高氧環境中潛在的危險

使用客戶名單

相關文獻

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?[2]Guijuan Chen,Kang Cheng,Yun Niu,Li Zhu,Xueting Wang.Epicatechin gallate prevents inflammatory response in hypoxia-activated microglia and cerebral edema by inhibiting NF-κB signaling.[J]Archives of Biochemistry and Biophysics ,Volume 729, 109393;

[3]Yapeng,LuPanpanChang,WangwangDing,JiangpeiBian,DanWang,XuetingWang,QianqianLuo,XiaomeiWu,LiZhu.Pharmacological inhibition of mitochondrial division attenuates simulated high-altitude exposure-induced cerebral edema in mice: Involvement of inhibition of the NF-κB signaling pathway in glial cells.[J] European Journal of Pharmacology,Volume 929,2022,175137

[4]Jun-Yu Wei, Miao-Yue Hu, Xiu-Qi Chen, Feng-Ying Lei, Jin-Shuang Wei, Jie Chen, Xuan-Kai Qin & Yuan-Han Qin .Rosiglitazone attenuates hypoxia-induced renal cell apoptosis by inhibiting NF-κB signaling pathway in a PPARγ-dependent manner, [J] European Journal of Pharmacology,Renal Failure, 44:1, 2056-2065

[5]Yilan Wang, Zherui Shen, Caixia Pei, Sijing Zhao, Nan Jia, Demei Huang, Xiaomin Wang, Yongcan Wu, Shihua Shi, Yacong He, Zhenxing Wang,Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling, [J] Biomedicine & Pharmacotherapy, Volume 156, 2022,113982

[6]Fang Zhao, Yan Meng, Yue Wang, Siqi Fan, Yu Liu,Xiangfeng Zhang, Chenyang Ran, Hongxin Wang and Meili Lu,Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway.[J] Frontiers in Pharmacology,10.3389/fphar.2022.920977

[7]Jing Zhang , Jian-Zhong Jiang , Jun Xu , Chen-Yu Xu , Shan Mao , Ying Shi , Wei Gu , Chun-Fang Zou , Yue-Ming Zhao , Liang Ye.”Identification of Novel Biomarkers for Abdominal Aortic Aneurysm Promoted by Obstructive Sleep Apnea”[J]Annals of Vascular Surgery, Available online 2 February 2023

[8]Zhang, C., Sun, Y., Guo, Y. et al. “JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension. “[J].Cell Death Discov. 9, 98 (2023).

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[11]Ma Jinqiu,Wang Chenyun,Sun Yunbo,Pang Lulu,Zhu Siqing,Liu Yijing,Zhu Lin,Zhang Shouguo,Wang Lin,Du Lina. "Comparative study of oral and intranasal puerarin for prevention of brain injury induced by acute high-altitude hypoxia" . [J] International Journal of Pharmaceutics,2020,591

[12]Jun-Yu Wei, Miao-Yue Hu, Xiu-Qi Chen, Feng-Ying Lei, Jin-Shuang Wei, Jie Chen, Xuan-Kai Qin & Yuan-Han Qin ."Rosiglitazone attenuates hypoxia-induced renal cell apoptosis by inhibiting NF-κB signaling pathway in a PPARγ-dependent manner" . [J]. European Journal of Pharmacology,Renal Failure, 44:1, 2056-2065

[13]Yilan Wang, Zherui Shen, Caixia Pei, Sijing Zhao, Nan Jia, Demei Huang, Xiaomin Wang, Yongcan Wu, Shihua Shi, Yacong He, Zhenxing Wang,"Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling" . [J]. Biomedicine & Pharmacotherapy, Volume 156, 2022,113982

[14]Yanfei Zhang, Jinyu Fang, Yingyue Dong, Huiru Ding, Quancheng Cheng, Huaicun Liu, Guoheng Xu, Weiguang Zhang“High-Altitude Hypoxia Exposure Induces Iron Overload and Ferroptosis in Adipose Tissue.” [J]. Antioxidants 2022, 11, 2367.

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[16]Xueting Wang, Yuqi Xie, Yun Niu, Baolan Wan, Yapeng Lu, Qianqian Luo, Li Zhu.CX3CL1/CX3CR1 signal mediates M1-type microglia and accelerates high-altitude-induced forgetting[J].2023-05-10 ,DOI:10.3389/fncel.2023.1189348

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