詳細介紹
1334237-71-6,AMG 416螯合劑
英文名:Etelcalcetide hydrochloride
(6R,9R,12R,15R,18R,21R,24S,29R)-24-Acetamido-1,29-diamino-12,15,18-tris(3-carbamimidamidopropyl)-6-carbamoyl-1-imino-9,21-dimethyl-8,11,14,17,20,23-hexaoxo-26,27-dithia-2,7,10,13,16,19,22-heptaazatriacontan-30-oic acid hydrochloride (1:1)
AMG 416
velcalcetide hydrochloride
etelcalcetide hydrochloride
KAI-4169
UNII:72PT5993DU
AMG-416
中文名:鹽酸依特卡肽
CAS:1334237-71-6
分子式:C38H73N21O10S2.xClH
分子量:1084.712
結(jié)構(gòu)式:
***質(zhì)量:1083.505737
描述:Etelcalcetide hydrochloride (AMG 416 hydrochloride) 是一種合成肽,有鈣敏感受體 (CaSR) 活化劑的作用。Etelcalcetide hydrochloride 可有效降低接受血液透析的繼發(fā)性甲狀旁腺功能亢進患者的甲狀旁腺*** (PTH) 濃度。
參考文獻:
[1]. Block GA, et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. JAMA. 2017 Jan 10;317(2):156-164.
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1334237-71-6,AMG 416螯合劑